Table 1.
Correlations between the expression of RP11-396F22.1 and clinical pathological parameters
| RP11-396F22.1 (%) | χ2 | P | ||
|---|---|---|---|---|
|
|
||||
| Clinicopathologic parameters | Low expression | High expression | ||
| Age (Year) | ||||
| ≤35 | 24 (88.9) | 3 (11.1) | 3.365 | 0.067 |
| >35 | 82 (71.9) | 32 (28.1) | ||
| Pathological grade | ||||
| Ia | 9 (90.0) | 1 (10.0) | 15.941 | 0.0012* |
| Ib1 IIa1 | 82 (82.0) | 18 (18.0) | ||
| Ib2 IIa2 | 9 (45.0) | 11 (55.0) | ||
| IIb | 6 (54.6) | 5 (45. 5) | ||
| Histological type | ||||
| Squamous carcinoma | 76 (70.4) | 32 (29.6) | 5.939 | 0.051 |
| Adenocarcinoma | 25 (92.6) | 2 (7.4) | ||
| Adeno-squamous carcinoma | 5 (83.3) | 1 (16.7) | ||
| Differentiation status | ||||
| Well | 15 (100.0) | 0 (0.0) | 6.921 | 0.0031* |
| Moderate | 44 (77.2) | 13 (22.8) | ||
| Poor | 47 (68.1) | 22 (31.9) | ||
| Tumor Size (cm) | ||||
| <4 | 91 (80.5) | 22 (19.5) | 8.739 | 0.0031* |
| ≥.0 | 15 (53.6) | 13 (46.4) | ||
| Invasion depth | ||||
| <1/2 | 58 (82.9) | 12 (17.1) | 4.394 | 0.036* |
| ≥.03 | 48 (67.6) | 23 (32.4) | ||
| Lymphatic vascular invasion | ||||
| Negative | 95 (77.2) | 28 (22.8) | 2.188 | 0.139 |
| Positive | 11 (61.1) | 7 (38.8) | ||
| Lymphatic Metastasis | ||||
| Negative | 95 (84.1) | 18 (15.9) | 24.118 | <0.001* |
| Positive | 11 (39.3) | 17 (60.7) | ||
| Squamous cell carcinoma antigen SCC | ||||
| ≤q | 58 (85.3) | 10 (14.7) | 3.787 | 0.0516 |
| >4 | 6 (60.0) | 4 (40.0) | ||
| HPV16/18 | ||||
| Negative | 11 (57.9) | 8 (42.1) | 0.258 | 0.612 |
| Positive | 63 (51.6) | 59 (48.4) | ||
*
indicate there is a statistical difference.