Figure 7.

miR-223 inhibits the PI3K/Akt signaling pathway. A. Representative western blots show the levels of p-AKT and total AKT (t-AKT) from cells treated with miR-223 mimic, miR-223 inhibitor, or negative controls. GAPDH was used as a loading control. Overexpression of miR-223 decreased expression of p-AKT in ASMCs relative to other groups. B. Data were normalized to GAPDH expression and presented as expression relative to untreated cellular controls. Data are means ± SD from three experiments (**P < 0.01; *P < 0.05).