Table 2.
Top 20 pathways related to the differentially expressed proteins (KEGG pathway analysis)
| Pathway | Differentially Expressed Proteins |
|---|---|
| Spliceosome | PRPF19 SF3B14 LSM3 SF3A2 DDX42 SART1 HNRNPU PRPF31 SFRS4_5_6 |
| Fluid shear stress and atherosclerosis | SUMO trxA TRPV4 SRC NOX CYBA argG IKBKG RELA |
| Protein processing in endoplasmic reticulum | HERPUD1 SYVN1 MARCH6 SEC61B UFD1 OS9 UBE2G2 BAX |
| Pathways in cancer | TPM3 BCR1 RALBP1 SMAD2_3 IKBKG BAX ARHGEF1 RELA |
| Viral carcinogenesis | SRC H2B DDX3X IKBKG MAPKAPK2 BAX RELA |
| Epithelial cell signaling in Helicobacter pylori infection | SRC ATPeV1G ADAM10 IKBKG F11R JAM3 RELA |
| HTLV-I infection | RRAS SMAD2_3 PPP3C IKBKG BAX RELA TSPO |
| PI3K-Akt signaling pathway | TSC2 EIF4B PPP2R5 IKBKG TSC1 RELA |
| Ubiquitin mediated proteolysis | PRPF19 UBE2Z SYVN1 UBE2L3 UBE3C UBE2G2 |
| Parkinson’s disease | UCHL1 COX5A ATPeF0F6 UBE2L3 QCR9 UBE2G2 |
| MAPK signaling pathway | SRC RRAS MAPT PPP3C IKBKG MAPKAPK2 RELA |
| Carbon metabolism | ALDO ENO OGDH PHGDH atoB ADPGK |
| Alzheimer’s disease | COX5A ATPeF0F6 ADAM10 MAPT QCR9 PPP3C |
| NOD-like receptor signaling pathway | TrxA NOX CYBA TRIP6 IKBKG RELA |
| Tight junction | PRKAB SRC SYNPO TJP3 JAM1 JAM3 |
| Proteoglycans in cancer | SRC PPP1R12B RRAS EIF4B PDCD4 ARHGEF1 |
| Phagosome | SEC61B NOX CYBA ATPeV1G MBL |
| Ribosome | RP-L28 RP-LP1 RP-S21 RP-L21 RP-L34 |
| mTOR signaling pathway | TSC2 ATPeV1G RRAGA_B EIF4B TSC1 |
| AMPK signaling pathway | PRKAB TSC2 PPP2R5 TSC1 HNF4A |