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Fold difference in Geometric Mean Titers of a trivalent HPV 16/18/58 vaccine (mid-dosage) over Gardasil quadrivalent vaccine.
| Sera sampling time from vaccinated rhesus macaques (weeks), i.e. post dose 3 |
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HPV type | 24 | 26 | 28 | 32 | 36 | 40 | 44 | 48 | 52 | 56 | 60 | 64 | |
| nAb titer | 16 | 1.9 | 7.6 | 3.4 | 2.7 | 3.1 | 2.1 | 4.2 | 2.5 | 2.4 | 1.5 | 2.5 | 2.6 |
| 18 | 8.3 | 11.3 | 12.3 | 9.1 | 8.8 | 9.8 | 9.3 | 10.5 | 11.1 | 10.2 | 12.8 | 13.7 | |
| IgG titer | 16 | 3.6 | 2.4 | 5.7 | 1.5 | 3.1 | 2.1 | 2.2 | 2.0 | 3.1 | 2.3 | 3.1 | 1.6 |
| 18 | 1.0 | 7.1 | 4.3 | 6.4 | 4.8 | 4.8 | 4.8 | 9.5 | 3.0 | 6.5 | 2.4 | 2.5 | |
