Fig. 1.

Effects of honokiol and temozolomide (TMZ) on the viability of human U87-MG glioma cells. After exposure to 1, 5, 10, 20, 40, 60, 80, and 100 μM honokiol for 72 h (a) and to 40 μM honokiol for 24, 48, and 72 h (b), the viability of human U87-MG cells was assayed using a colorimetric method. Human U87-MG cells were exposed to honokiol (40 μM), TMZ (100 μM), and their combination for 48 (c) and 72 h (d). Cell viability was assayed using a colorimetric method. Each value represents the mean ± SEM for n = 6. * and ^#, values significantly (p < 0.05) differ from the respective control and TMZ-treated groups