Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Apr 3;18:379. doi: 10.1186/s12885-018-4267-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 2 — Improved effects of honokiol on temozolomide (TMZ)-induced caspase-3 activation, DNA fragmentation, cell apoptosis, and cell necrosis. Human U87-MG glioma cells were exposed to honokiol (40 μM), TMZ (100 μM), and their combination for 72 h. The activity of caspase-3 was assayed using a fluorometric substrate method (a). DNA fragmentation was quantified with a cellular DNA fragmentation ELISA kit (b). Apoptotic cells were quantified using flow cytometry (c). Necrotic cells were determined with a photometric immunoassay (d). Each value represents the mean ± SEM for n = 6. * and ^#, values significantly (p < 0.05) differ from the respective control and TMZ-treated groups