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. 2018 Apr 4;18:53. doi: 10.1186/s12935-018-0549-4

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Effect of STAT3 down-regulation on cell migration in ECA109 cells. A Cell migration was determined by transwell assay after transfected for 72 h. The numbers of migration cells in five random microscopic fields (original magnification, ×200) were counted for each group. The results are an average of three independent experiments. B The mRNA relative abundance of MMP-9, uPA and SUSD2 were analysed by real-time PCR. Data shown represent the mean ± SE from three independent experiments.*P < 0.05, pSi-STAT3 group vs. pSi-Scramble