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. 2018 Apr 3;19:17. doi: 10.1186/s12868-018-0420-5

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Both 27-OHC and the proteasomal inhibitor MG-132 increase α-syn protein levels. Immunofluorescene imaging shows that both 27-OHC (E) and MG132 (I) increase the immunostaining of α-syn compared to control untreated cells (A). Staining with the Neuron Specific βIII-Tubulin marker in control (B), 27-OHC-treated (F) and MG132-treated (J) neurons. Staining with the nuclear counterstain DAPI in control (C), 27-OHC-treated (G) and MG132-treated (K) neurons. The overlay shows multiple neurons exhibiting nuclear α-syn staining (arrows) in 27-OHC (H) and MG132 (L) treated neurons compared to untreated neurons (D)