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. 2018 Apr 3;37:77. doi: 10.1186/s13046-018-0726-2

Fig. 5.

Fig. 5

Dying cell derived HMGB1 regulate tumor cell metastasis in vivo. a Selected images from the CT dataset of differently treated Panc-1 tumor model groups. Soft-tissue density nodules are clearly visible (arrowheads) in axial plane scanning. b Representative lung and mediastinal gross specimen from nude mice are shown. c HE staining was used to verify the lung and lymph node metastases foci. Magnification: × 4 and × 20