Figure 4.

Effects of Locomotion on Phasic Responses to Sensory Stimuli in V1, S1b, and Au

(A) The amplitude of the phasic response at the frequency of contrast reversal (4 Hz), imaged in an example session when the animal was stationary (left) or running (right).

(B) Time traces of VSFP signal in V1 evoked by 4 Hz contrast-reversing grating placed at 50-degree eccentricity, averaged across animals (n = 11). The first 400 ms of responses are shown. Values on the y axis indicate deviation of VSFP signal from its average before the grating stimulus. Blue trace shows time of stimulus reversal. Red and gray shading areas indicate SE across animals.

(C) Time traces of VSFP signal in V1 aligned by time of contrast reversal and averaged across the same animals as in (B). Values indicate deviation of VSFP signal from the average measured during stimulus presentation. Red and gray shading areas indicate SE across animals.

(D) Amplitude of the phasic response from all the imaging sessions, where one sample represents one animal. Colors denote the stimulation frequency (circles for Emx1-Cre mice and diamonds for Rasgrf-2A-dCre mice).

(E–H) Same as (A)–(D) for the VSFP signal evoked in S1b by trains of air puffs directed to contralateral whiskers.

(I–L) Same as (A)–(D) for the VSFP signal evoked in Au by trains of tones. Red symbols in (L) indicate responses in Au to air-puff stimulation.