Table 3.
Association between mgmiRs and clinicopathological characteristics in HNSCC tissues
| mgmiR9-1 %(n) |
mgmiR124-1 %(n) |
mgmiR124-2 %(n) |
mgmiR124-3 %(n) |
mgmiR129-2 %(n) |
mgmiR137 %(n) |
mgmiR148a %(n) |
Combined mgmiRs %(n) |
|
|---|---|---|---|---|---|---|---|---|
| Location | ||||||||
| OSCC (95) | 66.3(63) | 72.6(69) | 71.6(68) | 52.6(50) | 73.7(70) | 64.2(61) | 43.2(41) | 92.6(88) |
| OPSCC (44) | 75(33) | 72.7(32) | 86.4(38) | 50(22) | 79.6(35) | 61.4(27) | 40.9(18) | 97.7(43) |
| LSCC (48) | 56.3(27) | 68.8(33) | 81.3(39) | 43.8(21) | 68.8(33) | 58.3(28) | 50.0(24) | 89.6(43) |
| Smoking | ||||||||
| Never (37) | 70.3(26) | 67.6(25) | 73.0(27) | 56.8(21) | 64.9(24) | 59.5(22) | 51.4(19) | 89.2(33) |
| Current (50) | 74.0(37) | 76.0(38) | 86.0(43) | 44.0(22) | 74.0(37) | 64.0(32) | 36.0(18) | 96.0(48) |
| Ex (78) | 64.1(50) | 75.6(59) | 73.1(57) | 53.9(42) | 78.2(61) | 68.0(53) | 46.2(36) | 96.2(75) |
| HPV | ||||||||
| Positive (25) | 68.0(17) | 68.0(17) | 88(22) | 72(18) | 84.0(21) | 52.0(13) | 48.0(12) | 96(24) |
| Negative (41) | 51.2(21) | 63.4(26) | 65.9(27)* | 53.7(22) | 56.1(23)* | 61.0(25) | 39.0(16) | 80.5(33)* |
| Tumor size | ||||||||
| T1 (46) | 76.0(35) | 69.6(32) | 65.2(30) | 56.5(26) | 56.5(26) | 63.0(29) | 34.8(16) | 93.5(43) |
| T2 (49) | 65.3(32) | 77.6(38) | 87.8(43) | 51.0(25) | 83.7(41) | 65.3(32) | 53.1(26) | 95.9(47) |
| T3 (41) | 58.5(24) | 58.5(24) | 75.6(31) | 39.0(16) | 70.7(29) | 48.8(20) | 36.6(15) | 87.8(36) |
| T4 (50) | 62.0(31) | 78.0(39) | 80.0(40) | 52.0(26) | 82.0(41) | 68.0(34) | 50.0(25) | 94.0(47) |
| Node status | ||||||||
| N0 (78) | 69.2(54) | 79.5(62)* | 76.9(60) | 56.4(44) | 69.2(54) | 60.3(47) | 42.3(33) | 94.9(74) |
| N+ (108) | 63.0(68) | 65.7(71) | 77.8(84) | 45.4(49) | 76.9(83) | 63.0(68) | 45.4(49) | 91.7(99) |
| Stage | ||||||||
| I (34) | 73.5(25) | 73.5(25) | 64.7(22) | 55.9(19) | 55.9(19) | 58.8(20) | 32.4(11) | 91.2(31) |
| II (20) | 55.0(11) | 80.0(16) | 85.0(17) | 55.0(11) | 80.0(16) | 75.0(15) | 55.0(11) | 95.0(19) |
| III (59) | 67.8(40) | 66.1(39) | 74.6(44) | 44.7(24) | 72.9(43) | 59.3(35) | 37.3(22) | 91.5(54) |
| IV (73) | 63.0(46) | 72.6(53) | 83.6(61) | 53.4(39) | 80.8(59) | 61.6(45) | 52.1(38) | 94.5(69) |
*p < 0.05