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. 2018 Apr 3;37:76. doi: 10.1186/s13046-018-0739-x

Fig. 2.

Fig. 2

MiR-10a-5p promotes PDAC cell migration and invasion. a MiR-10a-5p overexpression promoted T3M4 and AsPC-1 cell migration, while miR-10a-5p knockdown decreased Su86.86 and AsPC-1 cell migration; b miR-10a-5p overexpression promoted T3M4 and AsPC-1 cell invasion, while miR-10a-5p knockdown decreased Su86.86 and AsPC-1 cell invasion; c miR-10a-5p expression up-regulation decreased E-cadherin and Caudin-1 protein levels while increasing Vimentin, Slug and Snail levels, as determined by using western blotting. d The relative intensity of the grayscale band values revealed the changes with miR-10a-5p overexpression or knockdown in PDAC cells; the data are presented as the means ± SD (Student’s t-test; *, P < 0.05)