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. 2018 Apr 3;18:377. doi: 10.1186/s12885-018-4103-5

Table 1.

Selected pathway categories associated with chemoradiation resistance by pathway enrichment analysis on genes with high expression variance

Pathway Number of genes
Cell cycle 62
MAPK signaling 87
p53 signaling 39
WNT signaling 48
Glutathione metabolism 23
TGF- β signaling 30
Insulin signaling 40
ErbB signaling 29
Phosphatidylinositol signaling 25
Mismatch repair 12
Inositol phosphate metabolism 20
JAK-STAT signaling 22
Apoptosis 25
VEGF signaling 22
Nucleotide excision repair 15