Table 3.
Univariate and multivariate Cox’s proportional hazards model analyses of prognostic factors for progression-free and overall survival
| Variable | Progression-free survival | Overall survival | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Univariate | Multivariate | Univariate | Multivariate | |||||||||
| n | n ∗ | HR | p(Wald) | HR | p(Wald) | n | n ∗ | HR | p(Wald) | HR | p(Wald) | |
| Prognostic groups1 | 79 | 79 | 3.41 | 3.00E-6 | 3.13 | 2.97E-5 | 269 | 181 | 1.63 | 1.45E-3 | 1.60 | 2.46E-3 |
| High-risk2 | ||||||||||||
| Age | 79 | 79 | 1.02 | 4.30E-2 | 1.01 | 3.70E-1 | 269 | 181 | 1.04 | 3.50E-8 | 1.03 | 6.12E-7 |
| MGMT methylation status | 79 | 79 | 1.33 | 2.14E-1 | 1,26 | 3.20E-1 | 269 | 181 | 1.68 | 6.59E-4 | 1.52 | 7.35E-3 |
| Unmethylated3 | ||||||||||||
∗Number of events; 1high-risk and low-risk groups; 2low-risk was used as reference; 3methylated was used as reference