Residue side chains involved in benzene unbinding. (a) Y88 and I78 (orange sticks) contribute to the blue and orange pathways. (b) F114, M102, and M106 (pink) contribute to the pink pathway. (c) M102, F153, R154, W126, and V111 (cyan) contribute to the cyan pathway. The benzene position in the crystal structure is shown in red sticks. The structure was rotated in each panel to allow a better view. To see this figure in color, go online.