Figure 1.

Effect of pressure on the secondary structure of microtubules in distinct morphological states. (A–F) Pressure-dependent normalized FTIR absorbance spectra (A–C) and second-derivative spectra (D–F) of the amide I′ band (1700–1600 cm⁻¹) for αβ-tubulin, microtubules, and MAP2c-bound microtubules at 37°C. (G–I) Temperature- and pressure-induced secondary structure changes are shown as normalized absorbance spectra. To see this figure in color, go online.