Table 4.
CYP3 A4, CYP3 A5 and ABCB1 genetic equilibrium test of genetic polymorphisms
| SNP | Number of examples (theoretical) | Genotype frequency | Allele frequency | χ2 | P |
|---|---|---|---|---|---|
| CYP3 A4 | |||||
| *1/*1 | 56 (59.29) | 0.56 | *1 = 0.77 | 3.45 | 0.06 |
| *1/*1G | 42 (35.42) | 0.42 | |||
| *1G/*1G | 2 (5.29) | 0.02 | *1G = 0.23 | ||
| CYP3 A5 | |||||
| *1/*1 | 8 (6.76) | 0.08 | *1 = 0.26 | 0.42 | 0.52 |
| *1/*3 | 36 (38.48) | 0.36 | |||
| *3/*3 | 56 (54.76) | 0.56 | *3 = 0.74 | ||
| ABCB1 C1236T | |||||
| CC | 10 (10.24) | 0.10 | C = 0.32 | 0.012 | 0.91 |
| CT | 44(43.52) | 0.44 | |||
| TT | 46 (46.24) | 0.46 | T = 0.68 | ||
| ABCB1 G2677 T/A | |||||
| GG | 13 (17.22) | 0.13 | G = 0.415 | 3.03 | 0.08 |
| GT/A | 57 (48.56) | 0.57 | |||
| AA/TT/TA | 30 (34.22) | 0.30 | T/A = 0.585 | ||