Figure 5.

The upper panel gives experimental and calculated Δε₂₂₀ (solid line) of the Aβ_1–9 peptide plotted as a function of temperature. The lower panel gives the experimental and calculated ³J(H^NH^α) (solid lines) values of the E3 (black) and D7 (red) residue. The dashed lines result from a calculation for which the NNI parameters associated with the E3 and D7 residues have been set to zero. The experimental data were retrieved from Danielsson et al. (27) The calculation is described in the text. The solid line results from the calculation with the NNI model described in the text. To see this figure in color, go online.