Table 1.
Mean ± SEM of Body Weight, Glucose level, Body mass index, Ovarian diameter, Ovarian weight, Diameter (μm), Peripheral granulosa layer thickness (μm), Theca layer thickness (μm) of secondary, tertiary and cystic follicle in Control
| Parameters | Control | PCOS | PCOS + Metformin | PCOS + Quercetin | |
|---|---|---|---|---|---|
| Initial Body Weight (gm) | 180.50 ± 1.82 | 180.33 ± 3.92 | 180.42 ± 1.85 | 180.14 ± 1.54 | |
| Final Body Weight (gm) | 199.25 ± 2.19 | 223.16 ± 3.85 | 193.51 ± 2.01 | 199.28 ± 2.75 | |
| Glucose (mg/dL) | 56.62 ± 0.48 | 72.20 ± 0.58 a*** | 56.22 ± 0.33 b*** | 56.14 ± 0.29 b*** | |
| Ovary diameter (mm) | 28.50 ± 1.08 | 68.16 ± 3.12 a*** | 29.72 ± 1.06 b*** | 33.85 ± 0.55 b*** | |
| Ovary weight (mg) | 3.63 ± 0.14 | 5.23 ± 0.11 a*** | 3.79 ± 0.07 b*** | 3.91 ± 0.10 b*** | |
| Secondary follicle diameter (μm) | 236.96 ± 15.06 | 270.42 ± 13.84 | 231.15 ± 14.94 b* | 217.72 ± 12.55 b* | |
| Granulosa layer thickness (μm) | 46.17 ± 1.39 | 50.83 ± 3.14 | 41.33 ± 1.06 | 41.83 ± 2.01 | |
| Theca layer thickness (μm) | 20.43 ± 1.22 | 21.82 ± 0.80 | 22.18 ± 1.02 | 21.02 ± 0.73 | |
| Tertiary follicle diameter (μm) | 419.10 ± 14.04 | 471.12 ± 15.77 | 414.22 ± 12.42 | 402.58 ± 15.48 | |
| Granulosa layer thickness (μm) | 52.34 ± 3.38 | 33.43 ± 6.10 a** | 53.53 ± 1.68 b** | 49.14 ± 2.20 b* | |
| Theca layer thickness (μm) | 25.01 ± 2.08 | 21.96 ± 1.32 | 23.95 ± 0.72 | 22.75 ± 0.88 a* | |
| Cystic follicle diameter (μm) | 0 ± 0 | 605.57 ± 7.61 a*** | 479.29 ± 20.77 b*** | 527.66 ± 26.05 b** | |
| Granulosa layer thickness (μm) | 0 ± 0 | 30.39 ± 1.22 a*** | 32.54 ± 3.20 a*** | 36.90 ± 3.61 a***b* | |
| Theca layer thickness (μm) | 0 ± 0 | 24.64 ± 0.90 a*** | 23.20 ± 0.52 a*** | 27.32 ± 2.31 a*** |
PCOS, PCOS+Metformin, PCOS+Quercetin treated groups after 21 days of experiment
Values are expressed as Mean ± SEM
*, **, *** indicate significance from the control group at P < 0.001, 0. 01 and 0.05 probability level