Table 2.
Mean ± SEM number of primordial, primary, secondary, tertiary, graffian, cystic, atretic follicle and corpus luteum (5 sections per ovary) in control, PCOS, PCOS + Metformin and PCOS +Quercetin treated adult female rats after 21 days of treatment
| Developing follicles (μm) | CONTROL | PCOS | PCOS + METFORMIN | PCOS + QUERCETIN | |
|---|---|---|---|---|---|
| Primodial | 7.80 ± 0.80 | 7.33 ± 0.38 | 8.14 ± 0.47 | 7.85 ± 0.42 | |
| Primary | 6.80 ± 0.33 | 5.50 ± 0.20 | 6.85 ± 0.40 b* | 6.90 ± 0.31 b* | |
| Secondary | 2.00 ± 0.89 | 0.60 ± 0.15 a* | 2.14 ± 0.24 b** | 2.00 ± 0.53 b* | |
| Tertiary | 1.61 ± 0.22 | 0.16 ± 0.15 a*** | 1.30 ± 0.17 b** | 1.28 ± 0.17 b** | |
| Graffian | 1.00 ± 0.63 | 0.16 ± 0.15 | 0.71 ± 0.17 | 0.85 ± 0.13 | |
| Cystic Follicle | 0 ± 0 | 11.33 ± 0.45 a*** | 1.57 ± 0.18 a**b*** | 1.60 ± 0.20 a**b*** | |
| Atretic Follicle | 2.80 ± 0.33 | 8.00 ± 1.82 a*** | 3.28 ± 0.26 b*** | 3.00 ± 0.20 b*** | |
| Corpus Luteum | 3.60 ± 0.35 | 1.66 ± 0.20 a*** | 3.57 ± 0.18 b*** | 3.43 ± 0.18 b*** |
Values are expressed as Mean ± SEM.*, **, *** indicate significance from the control group at P < 0.001, 0.01 and 0.05 probability level
aValue vs control, bValue vs PCOS