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CaM reverses the effect of Siah1a on group I mGluR-mediated calcium current inhibition. Bar graph illustrating average (+SEM) calcium current via the indicated receptor in cells expressing mGluR5b alone ("mGluR5b"), mGluR5b plus Siah1a ("+Siah1a") and mGluR5b + Siah1a and CaM ("+CaM"). The number of cells from each group is indicated in parentheses. * indicates a significant difference from control (p < 0.05, ANOVA). ** indicates a significant difference from "+Siah1a".
