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. 2018 Mar 28;9:292. doi: 10.3389/fphar.2018.00292

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Copyright © 2018 El-Agamy, Shaaban, Almaramhy, Elkablawy and Elkablawy.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of pristimerin (Pris) on Con A-induced alterations in (A). Oxidative stress and antioxidant indices: MDA, Malondialdehyde; SOD, Superoxide dismutase; GSH, Reduced glutathione; TAC, Total antioxidant capacity; (B). Nuclear factor erythroid-related factor 2 (Nrf2) mRNA expression and binding activity; heme-oxygenase-1 (HO-1) mRNA expression and level in hepatic tissue. Data are the mean ± SEM (n = 8). *P < 0.05, **P < 0.01, ***P < 0.001 vs. control group; ^##P < 0.01, ^###P < 0.001 vs. Con A group.