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. 2018 Mar 27;24:1776–1783. doi: 10.12659/MSM.909217

Table 3.

Age, gender, and plasma homocysteine levels in healthy controls and patients with rectal adenoma (low-risk and high-risk) and rectal cancer (Stage I–IV).

Characteristics Healthy (n=80) Low-risk (n=31) High-risk (n=54) Stage I (n=32) Stage II (n=38) Stage III (n=50) Stage IV (n=35) Chi square value/ t value p Value
Gender 1.403 0.966
 No. of male (%) 47 (23.7) 19 (9.6) 32 (16.2) 19 (9.6) 25 (12.6) 33 (16.7) 23 (11.6)
 No. of female (%) 33 (27.0) 12 (9.8) 22 (18.0) 13 (10.7) 13 (10.7) 17 (13.9) 12 (9.8)
Age (yr) 51.19 ±12.53 56.58 ±11.73 54.13 ±10.37 57.03 ±10.21 60.50 ±13.23 57.40 ±12.05 57.77 ±12.76 3.521 0.002
Hcy (μmol/L) 11.17 ±2.67a 13.12 ±3.25b 13.97 ±3.40b 14.45 ±4.65b 16.64 ±4.70c,d 17.19 ±5.47d 19.15 ±5.21e 21.893 <0.001

Values with a different superscript letter (a, b, c, d, e) have statistically significant differences between the groups. P<0.05.