Skip to main content
. 2016 Sep 16;1(2):109–121. doi: 10.1016/j.bioactmat.2016.09.004

Table 2.

Peptide inhibitors.

Peptide Amino acid sequence Type Target Reference
Anti-gp120 DGGNSNNESEIFRPGGGDMRDN Entry inhibitor HIV-1/gp120 [162]
Anti-CCR5 YQVSSPIYDINYYTSEPCQKINVKQIAA Entry inhibitor Co-receptor CCR5 [163]
PIE12-trimer HPXXCDYPEWQWLCXXELGK Entry inhibitor HIV gp41 N-trimer pocket [159]
PAW GTKWLTEWIPLTAEAEC RT inhibitor HIV-1 RT [179]
G12 GI-p-benzoylphenylalanine-FVSL Protease inhibitor ε-amino group of Lys 14 of HIV protease [205]
E1P47 WILEYLWKVPFDFWRGV Entry inhibitor HIV-1 Fusion Peptide [168]
p7 KETWETWWTE RT inhibitor Dimerization of RT [182]
Apam (2)-Tyr-Glu-T (4)-OH RT inhibitor HIV-1 protease dimer interface [180]
Vpr 57-71 VEAIIRILQQLLFIH RT inhibitor HIV-1 IN & RT [183]
Vpr 61-75 IRILQQLLFIHFRIG RT inhibitor HIV-1 IN & RT [183]
NYAD-1 HITFEDLLDYYGP-NH2 Gag inhibitor HIV-1 Gag polyprotein [245]
Vif peptide LITPKKIKPPLPSVT Vif inhibitor HIV-1 Vif [234]
p27 PQITLRKKRRQRRRPPQVSFNFCTLNF Protease inhibitor WT & PI resistant HIV-1 protease [190], [207]
Tetrameric peptide 10 ((ILPWKWPWWPWPP)2K)2K-NH2 Integrase inhibitor HIV-1 integrase [270]
Tetrameric RIN-25 ((ILPWKWPWWPWPP)2K)2K Integrase inhibitor HIV-1 integrase [209]