Figure 2.

Significantly enriched KEGG orthology (KO) pathways after 2 h and 8 h of imipenem exposure followed by growth in drug-free broth medium. Generally applicable gene-set enrichment (GAGE) analysis shows log₂ fold change (FC) ratios from low (green) to high (red) expression in significantly enriched KO pathways for imipenem-exposed compared to unexposed bacterial populations (three biological replicates in each sample group). A false discovery rate q-value cutoff ≤ 0.2 was applied. ^∗∗∗KO pathways with q-value of <0.1.