Table 1.
Body and muscle weights, morphometric cardiac characteristics, and pulmonary congestion in sham and HF rats after 8 weeks of exercise training.
| Groups | Sedentary | Trained | MD [95% CI] |
|---|---|---|---|
| BW, g | |||
| Sham | 347 (20) | 353 (24) | 6 [−22 to 34] |
| HF | 338 (28) | 352 (29) | 14 [−23 to 51] |
| MD [95% CI] | −8.8 [−53 to 36] | −0.8 [−29 to 28] | |
| HW/BW, mg/g | |||
| Sham | 2.69 (0.1) | 2.7 (0.1) | −0.01 [−0.1 to 0.1] |
| HF | 3.9 (0.1)* | 3.43 (0.4)† | −04 [−0.9 to 0.02] |
| MD [95% CI] | 1.2 [1 to 1.3] | 0.7 [0.2 to 1.2] | |
| RV/BW, mg/g | |||
| Sham | 0.56 (0.06) | 0.57 (0.15) | 0.01 [−0.1 to 0.1] |
| HF | 1.39 (0.2)* | 0.93 (0.37)† | −0.4 [−0.9 to −0.02] |
| MD [95% CI] | 0.8 [0.6 to 1] | 0.3 [−0.05 to 0.7] | |
| Pulmonary congestion, % | |||
| Sham | 73.6 (4.6) | 74.1 (1) | 0.45 [−3.9 to 4.8] |
| HF | 79.9 (0.9)* | 76.7 (1.2)† | −3.1 [−4.2 to −2.1] |
| MD [95% CI] | 6.3 [1.7 to 10] | 2.7 [1.5 to 3.9] | |
| Gastrocnemius, g | |||
| Sham | 1.92 (0.16) | 1.99 (0.22) | 0.07 [−0.1 to 0.3] |
| HF | 1.62 (0.18)* | 1.91 (0.26)† | 0.2 [−0.01 to 0.5] |
| MD [95% CI] | −0.3 [0.5 to −0.04] | −0.08 [−0.3 to 0.2] | |
| Gastrocnemius/BW, mg/g | |||
| Sham | 5.54 (0.4) | 5.63 (0.3) | 0.08 [−0.4 to 0.5] |
| HF | 4.8 (0.5)* | 5.4 (0.3)† | 0.5 [−0.07 to 1.2] |
| MD [95% CI] | −0.7 [−1.2 to −0.2] | −0.2 [−0.6 to 0.2] | |
Values are means (standard derivation); n = 7 for all groups. HF, heart failure group; BW, body weight; HW/BW, heart weight to BW ratio; RV/BW, right ventricle to BW ratio; MD, mean difference; CI, confidence interval.
*
p < 0.05 compared with Sed-Sham and Tr-Sham.
†
p < 0.05 compared with Sed-HF.