Table 4.
Zinc, Copper, CD4+ T-cells and Some Hematological Parameters of HIV-infected Subjects Based on Duration of Treatment
| Parameters | Duration of treatment |
p-value | |||
|---|---|---|---|---|---|
| 0–2 years | 3–5 years | 6–8 years | 9–12 years | ||
| (N = 31) | (N = 24) | (N = 12) | (N = 3) | ||
| Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | ||
| Hematology | |||||
| CD4 (cells/mL) | 278.58 ± 171.25 | 355.04 ± 262.97 | 430.25 ± 200.38 | 402.67 ± 247.13 | 0.04 |
| Hb (g/dL) | 12.51 ± 1.82 | 11.95 ± 1.28 | 12.03 ± 1.28 | 10.94 ± 0.33 | 0.49 |
| PCV (%) | 39.50 ± 4.81 | 38.00 ± 5.83 | 38.03 ± 3.00 | 35.00 ± 0.94 | 0.38 |
| MCV (fL) | 100.26 ± 10.11 | 96.46 ± 12.53 | 100.33 ± 10.86 | 92.93 ± 5.57 | 0.47 |
| RBC (×1012/L) | 3.95 ± 0.60 | 3.98 ± 0.65 | 3.82 ± 0.40 | 3.77 ± 0.16 | 0.82 |
| MCH (pg) | 27.58 ± 4.67 | 30.43 ± 5.47 | 31.88 ± 4.74 | 29.13 ± 1.55 | 0.63 |
| MCHC (g/dL) | 31.48 ± 11.92 | 31.33 ± 11.35 | 31.58 ± 10.37 | 31.33 ± 10.17 | 0.98 |
| WBC (×109/L) | 4.70 ± 1.58 | 4.81 ± 1.42 | 4.61 ± 0.83 | 5.53 ± 1.61 | 0.78 |
| Platelet (×109/L) | 233.32 ± 75.19 | 246.76 ± 78.11 | 240.33 ± 74.95 | 196 ± 76.38 | 0.75 |
| NEUT (×109/L) | 2.06 ± 0.94 | 2.11 ± 1.16 | 1.93 ± 0.53 | 2.87 ± 201.78 | 0.53 |
| LYM (×109/L) | 2.11 ± 0.80 | 2.04 ± 0.75 | 2.40 ± 0.72 | 2.03 ± 0.90 | 0.63 |
| MXD (×109/L) | 0.35 ± 0.55 | 0.57 ± 0.43 | 0.3 ± 0.34 | 0.63 ± 0.24 | 0.41 |
| Trace elements | |||||
| Zinc (μg/dL) | 77.40 ± 10.60 | 72.56 ± 8.98 | 72.72 ± 9.83 | 73.10 ± 11.66 | 0.28 |
| Copper (μg/dL) | 115.28 ± 4.35 | 101.80 ± 9.00 | 99.70 ± 9.56 | 97.7 ± 9.56 | 0.17 |
| Zn/Cu ratio | 1.74 ± 0.17 | 1.70 ± 0.16 | 1.67 ± 0.18 | 1.69 ± 0.19 | 0.90 |
N = absolute number; Hb = hemoglobin; PCV = packed cell volume; MCV = mean corpuscular volume; RBC = red blood cell; MCH = mean corpuscular hemoglobin; MCHC = mean corpuscular hemoglobin concentration; WBC = white blood cell; NEUT = neutrophil; LYM = lymphocyte; MXD = mixed cell; CD = cluster of differentiation.