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. 2017 Dec 2;9(1):20–26. doi: 10.1016/j.jaim.2017.01.005

Fig. 2.

Fig. 2

Mesostructure of sham-operated rats (A) and ovariectomized rats (B). Mesostructure of sham-operated rats presented rod-like trabecules with honeycomb appearance and minimal holes (A). Mesostructure of tibia bone in ovariectomized was rats significantly different as compared to sham-operated rats. Trabecular breaking and stump structure, which contributed to massive hole, and the losing of granule structure was observed in ovariectomized rats (B). The trabecular surface of ovariectomized rats supplemented with EECB12.5 or EECB50 was not different compared with ovariectomized rats (C, D), and the granule structure was seen in the third dose group (E) (Scanning Electron Microscope, Magnification ×2000).