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. 2017 Sep 25;9(1):63–80. doi: 10.1016/j.jcot.2017.09.010

Table 1.

Summary of the data from the recent studies on the use of megaprosthesis for the management of massive skeletal defects in proximal humerus.

Authors Diagnosis No of patients Average age (years) Average Follow up Clinical outcome Radiological Outcome Complications Result Survival
Dubina et al.9 Tumors 761 (30 studies) 45 70.5 MSTS = 74% 17% mechanical failure* 4% infection 10% revisions
Schmolders et al.10 Primary tumors and metastasis 30 (15 with trevira tube) 41 26 m EFS = 20 12 cranial migration of prosthesis 2 subluxations 3 revisions 83% at one year, 63% at 2 years
1 luxation and infection
1 RNP 1 recurrence 3 fractures
Marulanda et al.11 Malignancy 16 (Aortograft mesh) 51 26 m 1 superficial wound infection 1 death from disease

Abbreviations: EFS = Enneking Functional Score, RNP = Radial Nerve Palsy, m = months, *Mechanical failures including prosthetic loosening, fracture, and dislocation, CPS = Compliant Pre-stress Device, GH = Glenohumeral,PH = Proximal Humerus, SOH = Shaft of Humerus, DH = Distal Humerus.