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Dynamic or sink condition degradation profile of PLGA-Mg films. In vivo fluid clearance is simulated in vitro for the degradation of the PLGA-Mg composites at 47 C in PBS. Degradation media was changed every 7 days to simulate the normal sink conditions in vivo. The PLGA-Mg composites displayed a steady near neutral conditions throughout the duration of the study. The PLGA alone group displayed sharp decreases in pH (highlighted within red circles).
