Skip to main content
. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Pancreas. 2018 Apr;47(4):502–510. doi: 10.1097/MPA.0000000000001030

TABLE 2.

Somatic Mutational Changes

Gene Nucleotide (cDNA) Amino Acid Mutation Type Pathogenicity
PanNET high grade tumor area
 PTEN c.48T>A p.Tyr16Ter Nonsense Pathogenic
 SMAD4 c.1364A>C p.Gln455Pro Missense Pathogenic
 WRN c.2773G>A p.Ala925Thr Missense VUS
 CASC5 c.4162G>A p.Asp1388Asn Missense VUS
PanNET low grade tumor area
  None of significance

Somatic mutational changes identified in the high-grade and low-grade areas of tumor.