Figure 2.

LncRNA ZFAS1 inhibition suppressed CRC cells proliferation and invasion. (A) Relative expression of ZFAS1 measured by qRT-PCR in CRC cells and human colonic epithelial cells HCoEpiC. (B) ZFAS1 expression was examined by qRT-PCR assay in cells transfected with si-ZFAS1 or si-NC. (C) CCK-8 assay showed that ZFAS1 depletion inhibited the proliferation of SW480 and HT-29 cells. (D) colony formation assay revealed that ZFAS1 inhibition suppressed the clone formation of SW480 and HT-29 cells. (E) Transwell invasion assay suggested that ZFAS1 suppression inhibited the invasion ability of SW480 and HT-29 cells. *p<0.05