. Author manuscript; available in PMC: 2018 Nov 30.

Published in final edited form as: Cell. 2017 Nov 30;171(6):1340–1353.e14. doi: 10.1016/j.cell.2017.11.015

Table 1. Heritability estimates contrasting baseline skin pigmentation with tanning status.

SNP-based heritability estimates were computed with GCTA using genetic relationship matrices (GRMs) calculated from SNP gentoypes, an admixture-corrected GRM computed with REAP, and IBD segments. All models were unconstrained. See also Figure S1 and Table S3.

Method	Dataset	SNPs	N	h² (SE) baseline pigmentation^a	h² (SE) tanning status^b
GCTA GRM	genotype array	286,026	216	0.90 (0.15)	0.31 (0.19)
REAP GRM	genotype array	286,026	216	0.97 (0.15)	0.41 (0.21)
K_IBD	genotype array	NA	216	0.97 (0.16)	0.45 (0.22)
GCTA GRM	exome	117,132	82	0.95 (0.26)	0.37 (0.37)
SOLAR	pedigrees	NA	477	0.96 (0.12)	0.19 (0.11)

Bantu and European admixture proportions were included as covariates.

Age and sex were included as significant covariates for tanning status (wrist minus baseline underarm pigmentation).