Table 3.
Presence of Chlamydia trachomatis and Chlamydial Heat Shock Protein 60 in Ovarian Tumors
|
C. trachomatisa |
P | chsp60b |
P | |||
|---|---|---|---|---|---|---|
| n / N | % | n / N | % | |||
| Tumor characteristics | ||||||
| HGSC | 4 / 26 | 15.4 | 0.46 | 14 / 25c | 56.0 | 0.13 |
| Other tumorsd | 4 / 43 | 9.3 | 16 / 43 | 37.2 | ||
| Invasive EOC | 8 / 48 | 16.7 | 0.10 | 22 / 47c | 46.8 | 0.50 |
| Non-invasive tumorse | 0 / 21 | 0 | 8 / 21 | 38.1 | ||
Abbreviations: n / N = number of positive cases / total number of tumor subtype; HGSC = high-grade serous carcinoma.
a
C. trachomatis DNA analyzed with PCR.
b
Intense staining of nucleus was considered chsp60 positive.
c
One case was not evaluated due to technical problems with immunohistochemical staining.
d
Other tumors = endometrioid carcinoma, clear cell carcinoma, mucinous carcinoma, low-grade serous carcinoma, carcinosarcoma, mixed tumor, non-differentiated carcinoma, mucinous cystadenoma and borderline ovarian tumor.
e
Borderline ovarian tumor, n = 20; mucinous cystadenoma, n = 1.