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Photomicrography of the hippocampus of euthyroid rats (a, c) and thyroidectomized rats (b, d) at the third and fourth weeks after surgery, expression of PERK substrates pEIF2α (e) and CREB2 (f), and the PERK signal inhibitor GADD34 (g) in the hippocampus of euthyroid and thyroidectomized rats. Values are expressed as the mean ± SEM. ∗P < 0.05 versus the euthyroid group; ∗∗P < 0.05 versus the third week hypothyroid group (n = 3).
