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. 2018 Feb 20;11(2):426–435. doi: 10.1016/j.tranon.2018.01.022

Figure 1.

Figure 1

Higher antiprolifearive potency of nab-paclitaxel over paclitaxel in human esophageal adenocarcinoma cells. Human esophageal adenocarcinoma OE33 (A and B) and OE19 (C and D) cells were plated on 96-well plates and treated with (A and C) 1 nM to 5000 nM concentrations of nab-paclitaxel (NPT) (black points), paclitaxel (red points), carboplatin (violet points) and 5-flurouracil (blue points). Whereas in B and D, cells in 96 wells were treated with 1000 nM of paclitaxel (PT), carboplatin (CP) or nab-paclitaxel (NPT) alone or in combinations. After 72 hours, 10 μl WST-1 reagent was added in each well and incubated for 2 additional hours. The absorbance at 450 nm was measured using a microplate reader. The resulting number of viable cells was calculated by measuring absorbance of color produced in each well. Data are the mean ± SD of quadruplet determinations. * Represents NPT significantly different from Control, PT and CP; ** represents NPT+CP significantly different from Control, PT, CP, NPT and PT+CP.