Table 5.
Adjusted ORs (95% CI) for LGA by abnormal prepregnancy BMI and unrecommended gestational weight gain compared with normal-weight participants within IOM adherence guidelines among PPG (1978–1993) and CSL (2002–2008) cohorts
| IOM adherence | Prepregnancy BMI | n | Model I | P values | Model II | P values |
| OR (95% CI) | OR (95% CI) | |||||
| PPG | ||||||
| Within | Normal/underweight | 110 | 1.00 (reference) | 1.00 (reference) | ||
| Overweight/obese | 8 | – | – | |||
| Over | Normal/underweight | 83 | 1.61 (0.93 to 2.80) | 0.09 | 1.48 (0.83 to 2.64) | 0.18 |
| Overweight/obese | 58 | 2.04 (1.05 to 3.97) | 0.03 | 2.12 (1.11 to 4.04) | 0.02 | |
| CSL | ||||||
| Within | Normal | 56 | 1.00 (reference) | 1.00 (reference) | ||
| Overweight | 15 | 0.38 (0.08 to 1.81) | 0.23 | 0.53 (0.10 to 2.73) | 0.45 | |
| Obese | 23 | 1.86 (0.75 to 4.60) | 0.18 | 1.99 (0.79 to 5.01) | 0.15 | |
| Over | Normal | 82 | 2.14 (1.17 to 3.91) | 0.01 | 1.83 (0.99 to 3.40) | 0.06 |
| Overweight | 70 | 2.35 (1.26 to 4.40) | 0.01 | 2.25 (1.18 to 4.28) | 0.01 | |
| Obese | 49 | 1.26 (0.61 to 2.59) | 0.53 | 1.49 (0.70 to 3.19) | 0.30 |
BMI was defined as: underweight (BMI <18.5 kg/m2); normal (18.5 kg/m2≤BMI<25.0 kg/m2); overweight (25.0 kg/m2≤BMI<30.0 kg/m2); obese (BMI ≥30.0 kg/m2).
Insufficient LGA infants of overweight/obese women who remained within IOM guidelines to make LGA OR determination.
Model I: adjusted for age.
Model II: adjusted for model I+maternal race, parity, pre-eclampsia.
BMI, body mass index; CSL, Consortium on Safe Labor; IOM, Institute of Medicine; LGA, large-for-gestational age; PPG, Diabetes in Pregnancy Program Project.