Fig S3.

Protein-protein interaction networks of DEGs in cells infected with WT virus and nsp2TF/nsp2N-deficient mutants. Protein-protein interaction networks were constructed for all DEGs in cells infected with WT virus (A-B), vKO1 (C-H), and vKO2 (I-N) using the search tool for the retrieval of interacting genes/proteins (STRING). Confidence view of protein-protein interaction network from DEGs showing the strength of data support is indicated by the thickness of the grey line connecting genes and nodes. The representative pathways enriched in cells infected with WT virus (A-B), vKO1 (C-H), and vKO2 (I-N) were highlighted with red color.