Figure 2.

Facilitation is strongly attenuated in Syt7 KO animals at synapses made by granule cells onto PCs and SCs. Paired-pulse facilitation in wild-type and Syt7 KO mice. A, Representative paired-pulse facilitation at the grC to PC synapse in wild-type (top) and Syt7 KO (middle). PPR as a function of interstimulus interval (Δt) is summarized (bottom) for wild-type (n = 9) and Syt7 KOs (n = 10). Fits to single (solid) and double (dashed) exponential fits are shown. B, Same as in A, but at grC to SC synapses for wild-type (n = 6) and Syt7 KO (n = 7). Data are mean ± SEM. For some points error bars are occluded by markers.