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. 2018 Apr 4;13(4):e0194909. doi: 10.1371/journal.pone.0194909

Fig 4. Effects of substrate stiffness on d30 hiPSC-CM force production.

Fig 4

Data shown as mean ± SEM. A. Total force versus substrate elastic modulus (mean = 0.236 ± 0.02 μN, n = 21; 0.083 ± 0.01 μN, n = 15; 0.075 ± 0.01 μN, n = 22). B. Area versus substrate elastic modulus (mean = 754.9 ± 31.5 μm2, 702.3 ± 63.2 μm2, 851.6 ± 43.7 μm2). C. Normalized force versus substrate elastic modulus (mean = 32.4 ± 3.5 mN/mm2 x 10−5, 13.0 ± 2.1 mN/mm2 x 10−5, 9.1 ± 1.0 mN/mm2 x 10−5). D. Strain energy versus substrate elastic modulus (mean = 29.7 ± 4.3 fJ, 5.5 ± 1.7 fJ, 3.1 ± 0.6 fJ).