Table 3. Associations of physical activity and sedentary behavior variables with eGFRcrcys.
| Model 1 Beta (95%CI) |
Model 2 Beta (95%CI) |
Model 3 Beta (95%CI) |
Model 4 Beta (95%CI) |
|
|---|---|---|---|---|
| Total physical activity (h/day) | 2.30 (1.46; 3.14) | N/A | N/A | 1.55 (0.69; 2.40) |
| Lower intensity physical activity (h/day) | 2.10 (1.08; 3.12) | N/A | N/A | 1.49 (0.47; 2.50) |
| Higher intensity physical activity (10 min/day) | 0.70 (0.39; 1.02) | N/A | 0.53 (0.21; 0.85) | 0.31 (-0.02; 0.64) |
| Sedentary time (h/day) | -0.88 (-1.23; -0.53) | -0.71 (-1.08; -0.35) | N/A | -0.47 (-0.84; -0.10) |
| Sedentary breaks (10/day) | 0.93 (0.26; 1.61) | 0.80 (0.12; 1.47) | 0.59 (-0.10; 1.27) | 0.51 (-0.17; 1.19) |
| Prolonged sedentary bouts (#/day) | -0.96 (-1.32; -0.61) | -0.82 (-1.19; -0.46) | -0.66 (-1.23; -0.09) | -0.57 (-1.14; -0.01) |
| Average sedentary bout duration (min) | -0.41 (-0.57; -0.26) | -0.35 (-0.51; -0.20) | -0.27 (-0.45–0.08) | -0.23 (-0.41; -0.04) |
Note: Betas represent the difference in eGFRcrcys per one unit increase in the independent variable. Boldface indicates statistical significance (P <0.05). The associations in models 1 were adjusted for age, sex, glucose metabolism status, waking time, educational level, smoking behavior, alcohol consumption, energy intake, comorbid disease, mobility limitation; in models 2 the associations with the sedentary behavior variables were additionally adjusted for HPA; in models 3 the associations with HPA and the sedentary behavior pattern variables were additionally adjusted for sedentary time; in models 4 all associations were additionally adjusted for office systolic blood pressure, use of antihypertensive medication, waist circumference, total-to-HDL cholesterol ratio, triglycerides, use of lipid-modifying medication, prevalent cardiovascular disease. All analyses were based on complete cases (n = 2,258).
Abbreviations: CI, confidence interval; eGFRcrcys, estimated glomerular filtration rate based on serum creatinine and serum cystatin C; HPA, higher intensity physical activity; HDL cholesterol, high-density lipoprotein cholesterol, N/A, not applicable.