Table 2. Univariate and multivariate analyses of possible prognostic parameters for OS of GBM patients in the TCGA and REMBRANDT cohort.
Characteristic | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
TCGA cohort (n = 525) | ||||
ANGPT2 | 1.344 (1.103–1.637) | 0.003 | 1.015 (0.745–1.384) | 0.924 |
VEGFA | 1.260 (1.036–1.532) | 0.021 | 0.952 (0.712–1.273) | 0.740 |
ANGPT2*VEGFA | 1.524 (1.238–1.875) | <0.001 | 1.562 (1.021–2.388) | 0.040 |
REMBRANDT cohort (n = 151) | ||||
ANGPT2 | 1.212 (0.869–1.690) | 0.256 | ||
VEGFA | 1.261 (0.905–1.758) | 0.171 | ||
ANGPT2*VEGFA | 1.518 (1.055–2.185) | 0.024 |