Figure EV2. Chemical inhibitors of microtubule function attenuate signal but do not affect pathway variability.

We treated SGA85 cells with nocodazole and benomyl (Appendix), stimulated PRS activity with the indicated concentrations of pheromone, measured the accumulated fluorescent protein by flow cytometry, and computed η²(P) and P as detailed in Materials and Methods.

1. Plot shows P vs. dose.
2. Plot shows η²(P) vs. P.

Source data are available online for this figure.