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Potential inter-regulation of MSC-released miRNAs and ENaC subunits in re-alveolarization. MSCs as well as AT2 cells transfer the cytosolic materials in microvesicles to adjunct injured AT1 cells. miRs released by microvesicles would target the expression and activity of ENaCs, which in turn, regulate stem/progenitor cell homeostasis by altering proliferation and differentiation.
