Figure 3. Preclinical fractionated surgery and irradiation.
A, Preclinical mouse radiation protocol. B–F, (left) bioluminescence measurement of tumor growth. In parenthesis are the days (d) when treated tumor volume was significantly (p<0.05, non-parametric) less than control. (Right) survival curves of mice with indicated tumor types treated with fractionated irradiation or control. G, Preclinical combination mouse surgery and radiotherapy protocol. H–J, Bioluminescence measures of tumor growth (left) and survival curves (right) of mice with the indicated tumor types treated with surgery with or without fractionated irradiation (P values are Log Rank relative to control. Comparisons between treatments are Log Rank not significant (ns), P<0.005(**), P<0.0005(***), P<0.00005(****).
