Table 2.
PTa | LNb | |||||
---|---|---|---|---|---|---|
Patient | Amino Acid | EA Score | Typec | Amino Acid | EA Score | Typec |
1 | R248Q | 78.95 | HR | 0 | Wt | |
2 | R342* | Other | R342* | Other | ||
3 | E286A | 87.02 | HR | E286A | 87.02 | HR |
4 | 0 | Wt | 0 | Wt | ||
5 | 0 | Wt | L111fs, Y205C | 77.88 | HR | |
6 | G245S | 86.45 | HR | G245S | 86.45 | HR |
7 | 0 | Wt | 0 | Wt | ||
8 | L137fs | Other | L137fs | Other | ||
9 | 0 | Wt | 0 | Wt | ||
10 | Y107* | Other | Y107* | Other | ||
11 | 0 | Wt | 0 | Wt | ||
12 | R248Q | 78.95 | HR | R248Q | 78.95 | HR |
13 | Y220C | 72.52 | LR | 0 | Wt | |
14 | 0 | Wt | 0 | Wt | ||
15 | 0 | Wt | E285K | 69.87 | LR | |
16 | D207fs | Other | D207fs | Other | ||
17 | H179R | 81.91 | HR | H179R | 81.91 | HR |
PT: Primary Tumor
LN: Lymph Node Metastasis
TP53 mutations divided into 4 groups based on EA system: Wt (Wild Type), LR (Low-risk missense mutation), HR (High-risk missense mutation), Other (any type of mutations except missense mutations)