Table 1.

Clinical Regimens Used in Observational Studies for Treating Carbapenem-Resistant Klebsiella pneumoniae Where Carbapenemase Is Identified

β-Lactamases Present	Regimen	Improved Survival vs Monotherapy
KPC- and MBL- producing Klebsiella pneumoniae	•Carbapenem and tigecycline, plus aminoglycoside or colistin •Carbapenem and tigecycline •Carbapenem and aminoglycoside •Carbapenem and colistin	Yes
KPC-producing K. pneumoniae	•Colistin and aminoglycoside •Colistin and tigecycline •Colistin and quinolone •Colistin and carbapenem •Carbapenem and carbapenem	Yes

Abbreviations: KPC, Klebsiella pneumoniae carbapenemase; MBL, metallo-β-lactamase.