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. 2018 Apr 4;8:5618. doi: 10.1038/s41598-018-23918-x

Figure 1.

Figure 1

Transcriptomic analysis of Lmna−/− versus wild-type H-2K myoblasts expression profiles. (A) Volcano plot displaying the repartition of up- and down-regulated genes in Lmna−/− H-2K myoblasts compared to wild-type. Only the genes with a p-value inferior to 0.05 (−log10 p-value superior to 1.3) and at least a twofold change (log2 fold-change superior to 1) are displayed. (B,C) Clustergramm listing downregulated (B) and upregulated (C) genes were generated using ENRICHR (http://amp.pharm.mssm.edu/Enrichr/) to identify misregulated genes of interest in enriched GO Biological Process 2017 categories.