Fig. 5.
THZ1 inhibits 143B tumor growth in xenograft mice model. a, b Tumor growth of 143B xenografts (5 mice/group) treated with vehicle control or THZ1 were measured to evaluate the effect of THZ1. Data represent mean tumor volume ± SEM of different treatment groups (blue: vehicle control; brown: THZ1). Statistical significance was determined by Student t-test. *P < 0.05. c Immunohistochemistry staining of Ki67 in xenografts from subcutaneous transplantation of 143B cells into mice administered with vehicle control or THZ1. d The proportions of cells with positive staining of Ki67 in xenografts werequantified. Statistical significance was determined by Student t-test. ***P < 0.001.