Table 2.
Most significant, correlated and deregulated molecules after treatment.
| CluSO | Gene | Name | “Treated” group (n = 22) | Virus infected group (n = 2) | Inflammation group (n = 3) | Autoimmune group (n = 14) | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Regulation | logFCa | Regulation | logFCa | Regulation | logFCa | Regulation | logFCa | |||
| BE141 | RSAD2 | Radical S-Adenosyl methionine domain-containing protein 2 | Up | 2.52 (14)* | nsb | Up | 1.35 (1) | Up | 2.36 (4) | |
| BA153 | MX1 | Interferon-induced GTP-binding protein MX1 | Up | 1.92 (11)* | nsb | nsb | Up | 1.66 (4) | ||
| B7528 | IFI44L | Interferon-induced protein 44-like | Up | 2.99 (10)* | nsb | nsb | Up | 2.25 (7) | ||
| B7546 | IFI27 | Interferon-alpha inducible protein 27 | Up | 4.05 (10)* | Up | 2.25 (2) | nsb | Up | 4.04 (5) | |
| BI124 | BIRC4BP | XIAP associated factor-1 | Up | 1.54 (10)* | nsb | nsb | Up | 1.54 (3) | ||
| B7105 | HERC5 | Probable E3 ubiquitin-protein ligase HERC5 | Up | 1.96 (10)* | nsb | nsb | Up | 1.73 (6) | ||
| B7896 | ISG15 | Ubiquitin-like protein ISG15 | Up | 2.15 (10)* | Up | 1.33 (1) | nsb | Up | 1.98 (6) | |
| BF209 | SIGLEC1 | Sialoadhesin precursor | Up | 2.83 (10)* | Up | 1.95 (1) | nsb | Up | 2.88 (2) | |
| BF513 | SPATS2L | SPATS2-like protein | Up | 1.8 (9)* | nsb | nsb | Up | 1.76 (4) | ||
| BC522 | PLSCR1 | Phospholipid scramblase 1 | Up | 1.32 (9)* | nsb | Up | 1.10 (2) | Up | 1.58 (1) | |
| BH558 | USP18 | Ubl carboxyl-terminal hydrolase 18 | Up | 2.58 (9)* | nsb | nsb | Up | 2.41 (4) | ||
| B4753 | EIF2AK2 | Eukaryotic translation initiation factor 2-alpha kinase 2 | Up | 1.35 (9)* | nsb | nsb | Up | 0.15 (4)** | ||
| B7547 | IFI44 | Interferon-induced protein 44 | Up | 1.69 (9)* | nsb | nsb | Up | 1.88 (5) | ||
| B7549 | IFIH1 | Interferon-induced helicase C domain-containing protein 1 | Up | 1.44 (9)* | nsb | nsb | Up | 1.1 (4) | ||
| BB257 | OAS2 | 2′-5′-oligoadenylate synthase 2 | Up | 1.56 (9)* | nsb | nsb | Up | 1.63 (5) | ||
| B5174 | EPSTI1 | Epithelial stromal interaction protein 1 | Up | 1.69 (9)* | Up | 1.26 (1) | Up | 1.12 (2) | Up | 2 (2) |
*Molecules found to also be regulated in the opposite direction, shown in a single dataset; **Molecules found to also be regulated in the opposite direction, shown in 2 datasets; aNumber in brackets denote the number of significant occurrences in all samples; bNon-significant.